BGC > Produktsuche > Lapatinib ditasylate | 388082-77-7

Molecular Formula: C43H42ClFN4O10S3
Molecular Weight: 925.46
HS Code: 29420000

Description:
Lapatinib is a synthetic, orally-active quinazoline with potential antineoplastic activity. Lapatinib reversibly blocks phosphorylation of the epidermal growth factor receptor (EGFR), ErbB2, and the Erk-1 and-2 and AKT kinases; it also inhibits cyclin D protein levels in human tumor cell lines and xenografts. EGFR and ErbB2 have been implicated in the growth of various tumor types.

• Molecular Weight:925.46
• Melting Point:240-242°C
• Purity:>98%

Molecular Formula:
C29H26ClFN4O4S.2C7H8O3S
Canonical SMILES:
CC1=CC=C(C=C1)S(=O)(=O)O.CC1=CC=C(C=C1)S(=O)(=O)O.CS(=O)(=O)CCNCC1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl
InChI:
InChI=1S/C29H26ClFN4O4S.2C7H8O3S/c1-40(36,37)12-11-32-16-23-7-10-27(39-23)20-5-8-26-24(14-20)29(34-18-33-26)35-22-6-9-28(25(30)15-22)38-17-19-3-2-4-21(31)13-19;2*1-6-2-4-7(5-3-6)11(8,9)10/h2-10,13-15,18,32H,11-12,16-17H2,1H3,(H,33,34,35);2*2-5H,1H3,(H,8,9,10)
InChIKey:
UWYXLGUQQFPJRI-UHFFFAOYSA-N
Appearance:
Yellow Solid
Application:
Antineoplastic Agents
Synonyms:
GW-572016; GW 572016; GW572016

Purity: 98%
Smile code: O=S(CCNCC1=CC=C(C2=CC3=C(NC4=CC=C(OCC5=CC=CC(F)=C5)C(Cl)=C4)N=CN=C3C=C2)O1)(C)=O.O=S(C6=CC=C(C)C=C6)(O)=O.O=S(C7=CC=C(C)C=C7)(O)=O
MDL Number: MFCD09264195
MolFormula: C43H42ClFN4O10S3
MolWeight: 925.4608
Available in stock: 117.306

Smile code:
O=S(CCNCC1=CC=C(C2=CC3=C(NC4=CC=C(OCC5=CC=CC(F)=C5)C(Cl)=C4)N=CN=C3C=C2)O1)(C)=O.O=S(C6=CC=C(C)C=C6)(O)=O.O=S(C7=CC=C(C)C=C7)(O)=O
MDL Number:
MFCD09264195
Purity :
98%
Available in stock:
125.306 g